Exertional Compartment Syndrome

Topic updated on 08/28/15 9:47pm
  • A condition characterized by reversible ishemia to muscles within a muscular compartment
  • Epidemiology
    • incidence
      • second most common exercise induced leg syndrome
        • behind medial tibial stress syndrome
    • demographics
      • more common in males
      • often seen in 3rd decade of life
      • typically seen in runners or those who run a lot for their sport
    • location
      • anterior leg compartment most commonly affected (~70%)
      • anterior and lateral leg compartment affected in 10%
      • posterior leg compartment involvement associated with less predictable surgical outcomes
  • Pathophysiology
    • biochemistry
      • the local metabolism of the musculature cannot go fast enough to clear the metabolic waste products
    • pathoanatomy
      • vascular, advanced imaging, and histologic experiments have not provided clear evidence of the pathoanatomy of this condition
        • some investigators have found these patients to have a lower density of capillaries compared to asymptomatic individuals
        • fascial hernias have been identified with decompression
          • 40% of people with exertional compartment syndrome have these facial defects, only 5% of asymptomatic people have such defects
          • most common location is near the intramuscular septum of the anterior and lateral compartments, where the superficial peroneal nerve exits
  • Symptoms
    • aching or burning pain in leg
      • patients can often predict how long the pain will last for after they stop exercise
    • paresthesias over dorsum of foot
    • symptoms are reproduced by exercise and relieved by rest
      • symptoms begin ~ 10 minutes into exercise and slowly resolve ~30-40 minutes after exercise
  • Physical exam
    • normal
  • Radiographs
    • useful to eliminate other pathology
  • MRI
    • not very helpful in establishing diagnosis
    • can help eliminate other pathology 
  • Compartment pressure measurement
    • limb should be in relaxed and consistant position
    • required to establish diagnosis 
    • three pressure should be measured
      • resting pressure
      • immediate post-exercise pressure
      • continuous post-exercise pressure for 30 minutes
    • diagnostic criteria
      • resting (pre-exercise) pressure > 15 mmHg
      • immediate  (1 minute) post-exercise is > 30 mmHg and/or
      • continuous post-exercise failed to return to normal or remains > 15 mmHg at 15 minutes after cessation of exercise
  • Near-infrared spectroscopy
    • can show deoxygenation of muscle
      • showed return to normal within 25 minutes of exercise cessation
  • Nonoperative
    • activity modification
      • indications
        • rarely effective
    • anti-inflammatories
    • attempt these treatments for 3 months prior to operating
  • Operative
    • two incision fasciotomy
      • indications
        • refractory cases
      • technique
        • two incision approach
          • lateral incision
            • to release anterior and lateral compartments
            • 12-15 cm above lateral malleolus
            • identify superficial peroneal nerve and protect
            • may see fascial hernia
          • medial incision
            • used to release posterior compartments
            • perform if needed based on measurements
            • release  at middle of tibia at posterior border
          • endoscopic
            • smaller incisions, similar complications
      • outcomes
        • not a "home run" procedure because symptoms are often multi-variable
        • no studies directly comparing operative to non-opertative treatment options
        • successful treatment with surgery in 80+% of cases for the anterior compartment
          • deep posterior compartment success is lower (around 60%)
        • recurrence of symptoms in 2-15% of cases
  • Nerve injury
    • most commonly the SPN
  • DVT


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Qbank (1 Questions)

(OBQ05.82) An 18-year-old girl has bilateral leg pain. It occurs shortly after she begins running and is improved with rest. When she tries to continue running, she gets paresthesias on the dorsum of the foot. She has normal x-rays. What is the next step in evaluation? Topic Review Topic

1. Resting MRI bilateral tibiae
2. Venous doppler ultrasound
3. Non-invasive arterial vascular studies
4. Post-exercise compartment pressure measurement
5. Bone scan



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